2025 Research Award

Bedside Echocardiography in Thoracic Aortic Syndrome in the Emergency Department (BEaT-ED)

Chesterfield Royal Hospital NHS Foundation Trust Aortic Dissection Research
University of Derby aortic dissection research

Project Overview

While bedside ultrasound of the heart and aorta, known as transthoracic echocardiography (TTE), has the potential to support early diagnosis of Acute Aortic Syndromes (AAS), there is currently no national standard for how and when it should be used in suspected cases of AAS. A recent systematic review by Dr Nick Mani and his team has revealed major inconsistencies in the use of TTE and highlighted the urgent need to integrate this tool more effectively into clinical pathways alongside decision tools and biomarkers.

Improvement in diagnostic pathway of AAS is one of the James Lind Alliance top 10 priorities for research in emergency medicine.

This study aims to assess current TTE use across UK emergency departments and build expert consensus on best practice, including the role, timing, and selectiveness of bedside ultrasound in diagnosing AAS. In parallel, the research will explore how TTE can help rule in or rule out other serious conditions such as pulmonary embolism or heart attack, helping clinicians distinguish between similar emergencies with greater confidence and speed.

Key strategies include a national survey of emergency departments, followed by a Delphi process with clinical experts to agree on a standardised protocol. Public and Patient Involvement (PPI) will be central throughout. The ultimate goal is to improve diagnostic accuracy and safety, inform NHS training and education, and lay the groundwork for further research into enhanced emergency care for patients with suspected AAS.

Project Lead

Dr Nick Mani

Emergency Medicine Consultant

Dr Nick Mani is an Emergency Medicine Consultant at Chesterfield Royal Hospital with a clinical and academic focus on improving diagnostic pathways for cardiovascular emergencies. His research is dedicated to refining the use of imaging, decision tools and early interventions to support faster, safer diagnosis and treatment in acute care settings.

Dr Nick Mani aortic dissection

Co-Investigators

Dr Gerri Mortimore is an Associate Professor at the University of Derby with a clinical and academic background in Nursing and Advanced Practice, and expertise in running research across different healthcare sectors.

Miss Vittoria Sorice is a Senior Lecturer at the University of Derby and Advanced Practitioner at Chesterfield Royal Hospital with expertise in clinical and academic research with a focus on diversity and inclusion.

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Would you like to be part of this and future research projects? As a survivor, relative or family member who has lost a loved one to AD, your experience and opinion are vital.

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